Publications

Publications

Publications have been done at Karolinska Institute or at Uppsala University. Studies done by CIVD are highly confidential and are thus not published.

 

 

Nature. 2014 Apr 10;508(7495):215-21: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Gad H, Koolmeister T, Jemth AS, Eshtad S, Jacques SA, Ström CE, Svensson LM, Schultz N, Lundbäck T, Einarsdottir BO, Saleh A, Göktürk C, Baranczewski P, Svensson R, Berntsson RP, Gustafsson R, Strömberg K, Sanjiv K, Jacques-Cordonnier MC, Desroses M, Gustavsson AL, Olofsson R, Johansson F, Homan EJ, Loseva O, Bräutigam L, Johansson L, Höglund A, Hagenkort A, Pham T, Altun M, Gaugaz FZ, Vikingsson S, Evers B, Henriksson M, Vallin KS, Wallner OA, Hammarström LG, Wiita E, Almlöf I, Kalderén C, Axelsson H, Djureinovic T, Puigvert JC, Häggblad M, Jeppsson F, Martens U, Lundin C, Lundgren B, Granelli I, Jensen AJ, Artursson P, Nilsson JA, Stenmark P, Scobie M, Berglund UW, Helleday T.

 

 

Nature. 2014 Apr 10;508(7495):222-7.Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy. Huber KV, Salah E, Radic B, Gridling M, Elkins JM, Stukalov A, Jemth AS, Göktürk C, Sanjiv K, Strömberg K, Pham T, Berglund UW, Colinge J, Bennett KL, Loizou JI, Helleday T, Knapp S, Superti-Furga G.

 

 

J Pharm Biomed Anal. 2015 Feb;104:1-11. Development and validation of method for TH588 and TH287, potent MTH1 inhibitors and new anti-cancer agents, for pharmacokinetic studies in mice plasma. Saleh A, Gökturk C, Warpman-Berglund U, Helleday T, Granelli I.

 

 

Cell Cycle. 2013 Dec 15;12(24):3770-80. SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways. Gubanova E, Issaeva N, Gokturk C, Djureinovic T, Helleday T.

 

 

Am J Hypertens. 2007 Jul;20(7):743-50. Macrovascular changes in mice overexpressing human semicarbazide-sensitive amine oxidase in smooth muscle cells. Gokturk C, Sugimoto H, Blomgren B, Roomans GM, Forsberg-Nilsson K, Oreland L, Sjoquist M.

 

 

Micron. 2008 Jul;39(5):623-30. A novel method for quantification of the folding of elastic laminae in elastic arteries. Blomgren B, Göktürk C.

 

 

Biochem Biophys Res Commun. 2004 Dec 17;325(3):1013-20. Semicarbazide-sensitive amine oxidase in transgenic mice with diabetes. Gokturk C, Nordquist J, Sugimoto H, Forsberg-Nilsson K, Nilsson J, Oreland L.

 

 

Am J Pathol. 2003 Nov;163(5):1921-8. Overexpression of semicarbazide-sensitive amine oxidase in smooth muscle cells leads to an abnormal structure of the aortic elastic laminas. Göktürk C, Nilsson J, Nordquist J, Kristensson M, Svensson K, Söderberg C, Israelson M, Garpenstrand H, Sjöquist M, Oreland L, Forsberg-Nilsson K.

 

 

Mol Med. 2002 Dec;8(12):824-9. Semicarbazide-sensitive amine oxidase (SSAO) gene expression in alloxan-induced diabetes in mice. Nordquist JE, Göktürk C, Oreland L.

 

 

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